Yes. You can send a program officer an email, with a one page description/specific aims page (see funding opportunity announcement). Check the NLM website to identify the program officer listed for the particular program and the research area you are interested in. The program officer will read your description/Specific Aims page and tell you whether your project is within scope for the program, or may need further work. Please note that this will not be an in-depth evaluation of the scientific merit of the proposed project. We can only tell you if it is in scope; the scientific review will be carried out via the peer review process.