Your amended application must contain all the parts of the original application, plus an Introduction and be submitted within 37 months after the date of receipt of the original application. The Introduction to the revised application should summarize additions, deletions, revisions, and your responses to criticisms in the summary statement. All changes in the body of the research plan should be highlighted typographically, e.g., by bracketing, bolding, or italicizing. If the changes are so extensive as to include most of the text, this exception should be explained in the Introduction. If nothing has changed in the budget, resources section, or biosketches, you may use what was submitted with the original application. You should incorporate an updated description of any relevant work performed since the original submission, and updated letters of support. See deadlines for receipt dates for resubmissions.