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MedlinePlus is a full-featured consumer health web site. Users may access MedlinePlus through a web browser or a mobile device.

MedlinePlus Connect is a free service that allows electronic health record (EHR) systems to easily link users to MedlinePlus, an authoritative up-to-date health information resource for patients, families and health care providers. MedlinePlus Connect is not a replacement to MedlinePlus. It helps users of EHRs find health information from MedlinePlus.