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Only the Reviewer can request changes to the manuscript in NIHMS.

If you are the Reviewer, PMC-ready documents will be made available following conversion, at which time you may request necessary text-level edits, as well as corrections to figure, table, video, and supplemental files (see the NIHMS Overview for more information on the NIHMS process). 

Manuscripts missing title and author information or materials referenced in text (see What files should I submit to NIHMS? ) should be rejected at the Initial Approval step.